Medication Overuse Treatment Strategy Trial (MOTS)
The aim of this study is to compare two real-world strategies for treating patients who have chronic migraine with medication overuse, each with evidence for effectiveness:
- Transition from the overused acute medication used during migraine attacks to different acute medication (prescribed with parameters to avoid medication overuse) with optimized preventive treatment.
- Optimized preventive treatment without transition from the overused acute medication.
